DC-based startups that raised in the last 12 months and are actively hiring
Electrosoft is a cybersecurity and digital transformation services firm serving federal customers.
Theradaptive is a clinical-stage regenerative medicine company using a proprietary protein-engineering platform to create targeted therapeutics that drive bone regeneration.
Epic Padel is a Virginia-based company building and investing in padel clubs, technology, and leagues to accelerate the sport’s growth across the United States.
Sybal is a software company developing AI-powered governance solutions powered by its patented Proof of Governance (PoG) technology.
Remedy Plan Therapeutics is a clinical-stage biopharma developing hyperbolic NAMPT inhibitors (lead RPT1G) designed to partially inhibit disease-associated NAMPT to reduce healthy-tissue toxicity, advancing into Phase 1/2 AML/MDS trials.
Twenty develops intelligent, autonomous cyber warfare systems that accelerate the offensive cyber operations lifecycle for the U.S. military and Intelligence Community.
AuthMind's observability-driven identity protection platform continuously monitors human, non-human and agentic AI identities across cloud, hybrid, SaaS and on-prem, correlating flows, logs and context for threat detection.
Emerald AI builds software (the Conductor platform) that enables AI data centers to operate as power‑flexible, grid‑supportive assets.
Procurement Sciences AI provides an AI-native operating system that automates and optimizes the full lifecycle of selling to government agencies.
Virtru provides a data security platform built on the open Trusted Data Format, offering persistent, granular encryption and access controls across email, files, cloud apps, SDKs, and key-managed integrations.
HoloMD provides a clinician-supervised, AI-powered remote therapeutic monitoring platform that supports psychiatrists and their patients between visits.
Quantum Lending Solutions is a Reston-based fintech whose AI platform helps banks, marketplaces and technology platforms make smarter long-term lending decisions for small and medium-sized businesses.
Little Sesame produces chef-driven freshly spun hummus and snacks sold in ~3,000 US stores, certified organic/non‑GMO/Kosher, sourcing exclusively US organic regeneratively grown chickpeas and building an HPP plant.
Summit Ridge Energy develops, acquires, and operates community solar and battery storage projects across the U.S., managing subscriptions for residential and commercial customers.
Employee Navigator provides a unified benefits administration and HR platform licensed to insurance brokers, integrating with insurance carriers, payroll providers, TPAs, and a digital marketplace for brokers and employers.
Nanochon is a Washington, D.C.–based orthopedic device company developing Chondrograft™, a minimally invasive knee implant for treating articular cartilage defects.
Whitespace is a Belfast-based AI company providing a sovereign AI operating system, Collective, for defence, national security and other high-assurance regulated sectors.
The Security Bulldog provides an AI-driven cybersecurity intelligence platform that turns the firehose of open-source threat data into actionable insights for security teams.
Sublime Security is an AI-native email security platform that deploys specialized autonomous agents to detect, triage, and adapt defenses against sophisticated, rapidly evolving email threats.
HyperSpectral develops an AI-powered spectral intelligence platform that delivers rapid, non-invasive pathogen detection and other material insights for medtech, food safety, and defense applications.
Bricklayer.ai provides an agentic AI platform that automates and scales cybersecurity operations for Security Operations Centers.
Syntracts provides an on-prem, API-first contract intelligence platform that turns firms’ legacy contracts into structured, searchable data to power private, verifiable legal AI workflows.
Curio develops NuCycle, an advanced nuclear fuel recycling technology that increases resource recovery, minimizes waste, and embeds security in used-fuel processing.
PediaMetrix develops SoftSpot, an FDA-cleared mobile app that uses smartphone cameras, computer vision, and AI to provide point-of-care quantitative cranial measurements and monitoring for infant head-shape abnormalities.
KnowledgeNet.ai offers an AI-powered outbound intelligence platform that transforms fragmented customer data into actionable revenue-generating insights for sales teams.
JuneBrain is a Baltimore-based neurotech company that develops portable retinal imaging headsets and AI-based optical coherence tomography software to monitor neurological disease.
Ressio Software provides an AI-powered construction management platform for residential builders and remodelers.
Nowy is an AI-powered travel platform that processes social media travel content to assemble personalized, bookable itineraries.
Parlay offers a SaaS Loan Intelligence System that integrates with origination systems to automate small-business/SBA onboarding, eligibility verification, AI decisioning, and product matching for community banks and credit unions.
Spear AI supplies maritime AI via the Horizon acoustic-data platform, modular edge-deployable sensors, and technical services for AI strategy, data pipelines, algorithms, MLOps, and operational integration for U.S. Navy/DoD.
UgenticAI acquires and integrates agentic AI companies, providing centralized resources to develop autonomous software agents that manage SMB business functions (sales, content, support) while enabling portfolio scaling.
Kovr.ai provides an AI-native cyber compliance automation platform for cloud and hybrid environments that automates FedRAMP/CMMC via code-driven intelligence, automated SSP generation, AI assistant, audit-ready documentation, and DevOps integrations.
Area 2 Farms builds and operates organic, soil-based indoor farms embedded within local communities to shorten the food supply chain.
ODRG provides emerging-technology solutions to U.S. defense, intelligence, and federal agencies, specializing in AI-powered geospatial intelligence, human-centered design, secure-by-design cloud services, process automation, and software partnerships.
Silent Push provides a preventive threat-intelligence platform that detects cyberattacks in advance using Indicators of Future Attacks (IOFA).
BITE Data is an AI-native SaaS company that automates global trade compliance workflows for importers and exporters.
Overview Energy is developing space-based solar arrays that beam power via infrared lasers to existing utility-scale solar farms on Earth for near-continuous renewable energy generation.
Rhino.ai provides an AI-powered platform that automizes the full modernization lifecycle of legacy enterprise systems into agile, scalable architectures.
VanishID (formerly Picnic) provides agentic AI-driven OSINT monitoring and remediation for enterprises, mapping public data from 1,000+ sources to protect executives' devices and social accounts from social engineering.
ClearVector provides an identity-driven security platform that traces and controls machine, third-party, and AI identities across cloud, SaaS, and control planes with a patented identity graph and real-time mitigation.
ARC Clean Energy develops the ARC-100, a 100 MWe sodium-cooled advanced small modular nuclear reactor that delivers safe, carbon-free power for grids, heavy industry and AI data centers.
ARCYN Defense develops edge-AI-powered air and counter-threat defense systems built for contested, modern battlefields.
Obviant ingests and unifies thousands of OSINT and customer data sources—program documents, budget justification books, Congressional reports—using AI to map DoD acquisition, contracting, budgeting, opportunities, and program-level analyses.
WizCommerce is an AI-powered commerce platform for wholesale distributors that provides AI quoting, personalized storefronts, product-content generation, a sales assistant and image-generation tools for front- and back-office functions.
A startup developing artificial-intelligence technology for the real-estate sector.
Rhizome provides a cloud-based AI/ML climate-resilience planning platform for utilities—gridADAPT, gridFIRM, and gridCAVA—that maps asset-level climate risk, prioritizes infrastructure upgrades, and supports wildfire mitigation.
Aledade operates the nation’s largest network of independent primary care practices, helping clinicians succeed in value-based care arrangements through technology, data analytics, and payer contracting support.
Higher Medicine is developing epigenetic therapies aimed initially at Kabuki syndrome with plans to address additional central nervous system disorders such as CTE and Alzheimer’s disease.
SciNeuro Pharmaceuticals is a biotech company developing therapies that target multiple disease pathways involved in neurodegenerative disorders such as Alzheimer’s and Parkinson’s.
GenLogs is an AI-powered supply-chain intelligence company that uses nationwide roadside sensors, satellites, and other data streams to deliver real-time visibility and security for U.S. trucking operations.
Shift5 builds a protocol-agnostic hardware and software OT cybersecurity platform that captures onboard serial-bus data, delivers edge intrusion detection, firmware attestation, and predictive maintenance for military and commercial fleets.
LucyRx is an independent PBM offering technology-enabled prescription benefits: integrated specialty network, formulary marketplace, next-day home delivery, and LucyIQ AI analytics, supported by U.S.-based pharmacy technicians.
Last Energy develops steel-encased small modular nuclear reactors designed to generate 20 MW of electricity.
BriefCatch is an AI-assisted legal-writing platform that integrates with Microsoft Word to give lawyers real-time editing and clarity improvements.
Sorcero provides an AI-powered intelligence platform that helps life-science companies rapidly generate and apply medical evidence to drive physician engagement and therapy adoption.
Rune Technologies builds TyrOS, an edge-first, hardware-agnostic AI logistics OS for contested military supply operations that forecasts demand, optimizes resource allocation, supports disconnected operations, and integrates planning algorithms.
Trusted Space provides full life-cycle space mission engineering solutions that enable secure, real-time command-and-control for proliferated satellite constellations.
Zeno Power develops compact radioisotope power systems using strontium-90 heat sources for seabed infrastructure, maneuverable satellites, and lunar landers, with demonstrated prototypes tested at Pacific Northwest National Laboratory.
MPOWER Financing is a Washington, D.C.–based fintech that provides education loans to international students attending U.S. and Canadian universities.
Lightshift Energy develops, owns, and operates utility-scale battery energy storage and integrated grid storage projects across the U.S., providing storage analytics, application design, financing, development, and multi-use project deployment.
X-energy develops high-temperature gas-cooled small modular nuclear reactors (SMRs) to supply flexible, carbon-free power.
Ignium is a U.S.–headquartered merchant provider that supplies mission-critical software, power, and energetic subsystems for current and next-generation weapons platforms used by the U.S. and allied defense forces.
Chamber Cardio provides an AI-powered data and intelligence platform that helps cardiologists and health plans deliver value-based cardiovascular care.
Bluprynt provides an enterprise-grade compliance operating system that links off-chain regulatory requirements with on-chain identity and policy for digital-asset issuers, banks, and other financial institutions.
Interos.ai is an Arlington-based platform that uses artificial intelligence to monitor and manage supply-chain risk and operational resilience.
Branded Realities builds AR/AI-powered platforms that let sports fans create personalized, shareable content by posing with their favorite athletes.
Helios AI develops AI-powered software that forecasts agricultural commodity prices and provides supply-chain insights for food industry stakeholders.
Trustible provides an AI governance platform that centralizes oversight across internal and third-party systems, offering continuous AI risk measurement, compliance management, embedded workflows, taxonomies, recommendation models, and in-app guidance.
Jito builds validator software, a liquid staking token (JitoSOL), and other open-source infrastructure that boost performance and staking rewards on the Solana blockchain.
Cape is a privacy-focused cellular network provider offering device and mobile network solutions to government, enterprises, and consumers.
Moonbounce is a content-moderation company that turns policy documents into executable runtime guardrails using a proprietary LLM.
Valinor Enterprises is a Washington, D.C.–based operational holding company that builds and acquires defense-focused technology “Product Companies” through a centralized infrastructure and decentralized engineering model.
Tidal Cyber provides a SaaS threat‑informed defense platform that maps MITRE ATT&CK, third‑party and internal intelligence to produce confidence scores, coverage maps, and prioritized remediation guidance.
Lovelytics is an Arlington-based AI-focused data and analytics consulting firm that helps enterprises design and implement Databricks-powered AI and data strategies.
Cove provides a unified property-operations platform and white-labeled tenant portal—linking tenant experience, building OS, access control, work-order and amenity booking—and operates tech-enabled neighborhood coworking locations.
Hydrosat delivers thermal-infrared satellite data and AI-powered analytics that help governments, agribusinesses and defense organizations monitor water use, crop health and other resource pressures.