Domilise's Po-Boy & Bar • 1924

From a small yellow house on the corner of Annunciation and Bellecastle, the scent of fried shrimp and oysters drifts through Uptown each afternoon. Peter and Sophie Domilise opened this neighborhood bar in 1918, and a century later their great-grandchildren still pile crispy seafood onto fresh Leidenheimer bread, drawing politicians, Tulane students, and anyone who knows the po-boy is best eaten hot, fully dressed, at the counter.