NC-based startups that raised in the last 12 months and are actively hiring
CollegePlannerPro provides a cloud-based practice management platform for independent educational consultants to streamline student advising and college admissions workflows.
Atlantic Fish Company develops cultivated seafood using cellular agriculture to offer sustainable alternatives to overfished species.
Levitate provides an AI-powered relationship marketing platform that helps relationship-based small businesses maintain personalized, scalable client outreach.
NetFoundry provides identity-driven, zero-trust networking software that embeds identity, authorization and policy controls directly into network overlays.
Looma is an in-store retail media platform that uses co-located video screens to provide storytelling, education, and personalized product recommendations at the point of purchase.
Scale Social AI turns authentic, customer-generated content into localized digital ads for franchises and multi-location brands.
Deep Blue Medical Advances is a surgical device company developing the T-Line Mesh, Suture, and Aesthetic Scaffold product lines to improve soft tissue surgery outcomes.
FG Nexus manages and tokenizes digital and real-world assets while building sizeable on-balance-sheet crypto reserves.
Beroe is a procurement decision-intelligence platform that provides AI-driven market insights to more than 1,000 global enterprises.
Plantd develops advanced production technologies for carbon-negative building materials.
Cycle Labs delivers an end-to-end continuous test-automation platform that enables enterprises to validate complex supply-chain software and operations.
Rebelstork, operating as REBEL, runs North America’s largest B-Corp certified returns recommerce marketplace that resells open-box and overstock goods at up to 70% off retail prices.
Teamworks provides a centralized operating system for sports and tactical organizations that unifies recruiting, athlete development, performance, scheduling, communication, compliance, payments, and analytics across web and mobile.
Vantaca is an AI-first community association management platform that automates and streamlines finance, communication and resident-service workflows for property management companies.
ClinTrial Research operates an AI-enabled clinical site network designed to improve trial execution and patient care.
Franzy is an AI-powered marketplace that matches prospective franchisees to brands using proprietary Fit Score, hosts 3,000+ brand profiles, provides due-diligence materials and coaching, and plans a resale marketplace.
Locus Biosciences is a Morrisville, NC–based clinical-stage biotechnology company engineering AI-designed bacteriophage therapies to combat antibiotic-resistant bacterial infections.
Keebler Health is an LLM-native health technology company that processes unstructured clinical documentation to surface missed HCC coding opportunities for value-based care.
Flywheel provides a cloud-based medical imaging data management and analysis platform used by pharmaceutical companies, medical device makers, and academic medical centers.
Extellis is a satellite-imaging startup developing metasurface-antenna synthetic-aperture radar (SAR) satellites to deliver affordable, reliable, all-weather Earth observation at industrial scale.
Ten63 Therapeutics is an RTP-based biotech using a large quantum-chemistry AI platform to design small-molecule drugs against historically “undruggable” protein targets.
TruTechnologies provides a real-time clinical trial oversight platform, TruLab, with mobile protocol-driven oversight, sample tracking, risk-based monitoring, TruDose dosing compliance, and TruScreen screening visibility for pharma, CROs, sites.
Opine provides an AI-native unified workspace that streamlines complex B2B technical sales from presales through post-sales handoff.
The Ammortal Chamber is an advanced wellness technology designed to optimize human performance, enhance longevity, and promote holistic health through a unique combination of non-invasive, scientifically-proven bio-energetic technologies.
Whip Around provides fleet maintenance and compliance software that digitizes vehicle inspections for trucking and other commercial fleets.
SonoVascular is a Chapel Hill-based clinical-stage medical device company developing the ultrasound-facilitated SonoThrombectomy System to safely and effectively remove blood clots in venous thromboembolism patients.
ReFiBuy is a startup building infrastructure to make product data usable for agent-driven commerce and coined the term "Agentic Commerce Optimization."
IperionX develops technology to convert raw materials into titanium metal and powders, integrating additive manufacturing to build a secure U.S. titanium supply chain for aerospace, defense, and medical markets.
Evecxia Therapeutics is a biopharmaceutical company developing serotonin-synthesis-amplifying therapies for central nervous system disorders such as obsessive-compulsive disorder (OCD) and major depressive disorder (MDD).
Slate Medicines is a Raleigh-based biotech developing anti-PACAP antibody therapies for migraine and other headache disorders.
N3XT is a blockchain-focused bank building financial services for the digital asset economy.
Vega Health provides a curated marketplace and integration platform that helps health systems adopt, implement, and monitor validated AI solutions.
Folio is a procure-to-pay platform for hotels that combines a managed marketplace (Folio Buy), AI-powered invoice processing (Folio Bills), and streamlined payments (Folio Pay) with rapid implementations.
TARGAN develops technologies—such as its WingScan platform—that address key challenges in global food production.
Sunseeker is a Zhejiang-based robotics firm that designs and manufactures AI-enabled autonomous lawn-mowing robots for consumer and commercial outdoor maintenance.
Flexential operates FlexAnywhere, a distributed data center platform providing colocation, cloud services, connectivity, data protection and high-density GPU support across 40+ U.S. data centers and 18 markets.
Eton Solutions' AtlasFive is a wealth-management ERP platform consolidating data, services and workflows for family offices, PE firms, funds, RIAs and private banks, enabling investment, accounting, reporting, AI automation.
Fastbreak AI provides AI-driven scheduling and operations software for professional sports leagues worldwide.
Turgo.ai provides an AI-powered marketing execution platform that automates up to 80% of end-to-end marketing tasks for growth teams.
Positec is a global power tools company (brands Worx and Kress) focused on battery-powered tools and robotics.
iOrganBio develops CellForge™, an AI-driven platform for precise, scalable manufacturing of human cells and organoids.
Revian develops an FDA-cleared, app-integrated red-light therapy cap that promotes hair regrowth for men and women.
Truentity Health is a Chapel Hill startup operating an AI-powered clinical care delivery network that enables community pharmacies to deliver and manage reimbursable chronic care services.
RevelAi Health provides a conversational-AI virtual care navigator for orthopedic practices that triages, collects voice/text outcomes, generates coded clinical documentation from encounters, flags risks, and triggers episode-wide care workflows.
Opex Technologies advises enterprise and mid-market clients on technology procurement and implementation, sourcing and managing cloud, data center, security, network, AI, collaboration, voice, CX, and other managed solutions.
Unifyr provides an AI-driven software platform that helps enterprises manage and scale complex partner ecosystems across marketing, sales, and revenue operations.
Sennos is a company providing AI-driven sensing, precision hardware, analytics, and automation for the fluidics and fermentation industries.
Futureproof is an AI-powered financial intelligence platform that gives startup founders real-time, CFO-level visibility into their finances.
Lucid Bots is a company that designs, manufactures and supports autonomous exterior cleaning hardware and a subscription RaaS platform.
Alleviate Health provides human-in-the-loop AI agents that automate and accelerate patient recruitment for clinical research sites.
EnrollHere is an AI-powered platform and system of record for insurance distribution serving Medicare Advantage agencies, field marketing organizations, and carriers.
Belhaven Biopharma is a clinical-stage pharma company developing dry‑powder, single‑use nasal delivery systems—including Nasdepi, a heat‑stable, needle‑free epinephrine therapy for emergency anaphylaxis—based in Raleigh, NC.
restor3d designs and manufactures 3D-printed patient-specific musculoskeletal implants and disposable instruments, combining AI-driven surgical planning software with in-house additive manufacturing and osseointegrative materials.
Old Well Labs (OWL) offers an AI-powered data platform that helps institutional allocators and investment managers discover, monitor and connect with each other.
Incyclix Bio is a next-generation cell cycle control company developing INX-315, a potent and selective CDK2 inhibitor for advanced and resistant cancers.
KLIK SaaS provides a cloud-based platform that lets organizations create, manage, and monetize branded online communities.
GeneCentric develops GenomicsNext, an integrated liquid‑biopsy platform combining ctDNA variant detection and ExpressCT-derived gene‑expression measurements, plus rT(I)ME Explorer and AI tools to identify oncology responder signatures for biopharma collaborations.
Postbiotics, Inc. develops clinically validated postbiotic products that target gut health, age-related disease, and longevity.
Cloneable is an AI automation company that captures institutional knowledge and deploys specialized agentic AI for infrastructure operations.
SetSale is an AI-powered sales platform for the residential HVAC industry that embeds real-time pricing, inventory, rebates, and financing into the proposal workflow.
DG Matrix develops solid-state transformer technology that routes and conditions power more efficiently for data centers and other high-density electrical applications.
Save is a Houston-based fintech that offers a market-driven cash management platform combining FDIC-insured deposits with market-linked yield potential.
Brightspeed operates a XGS‑PON fiber broadband network across 20 U.S. states, delivering symmetrical multi‑gig internet to residential and business premises and supporting over 7.3 million addresses.
Javara embeds research teams and centralized operations within healthcare systems to conduct clinical trials at the point of care, accelerating study start-up, enrollment, diversity, and data quality.